Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.60 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | FTO | Q9C0B1 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 2/20 | 0.60 |
| ▸ | GABRP | O00591 | 4/20 | 0.58 |
| ▸ | GABRD | O14764 | 4/20 | 0.58 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4783697 | 0.88 | ALDH1A1 (0.67) | MEN1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL28066043 | 0.82 | GABRP (0.65) | MEN1MAPTKMT2ASMN1; SMN2CYP1A1 | |
| SCHEMBL30738943 | 0.79 | ACHE (0.73) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| Norwogonin SCHEMBL760431 | 0.79 | GABRP (0.68) | MEN1MAPTKMT2ASMN1; SMN2GAA | |
| Norwogonin SCHEMBL30485998 | 0.79 | GABRP (0.68) | MEN1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL12835534 | 0.78 | ABCB1 (0.55) | MEN1MAPTKMT2ASMN1; SMN2CYP1A1 | |
| SCHEMBL17786501 | 0.78 | MAPT (0.66) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL17786515 | 0.78 | ABCB1 (0.67) | MEN1MAPTKMT2ASMN1; SMN2NPC1 | |
| SCHEMBL27719536 | 0.77 | PPARG (0.68) | MEN1MAPTKMT2ASMN1; SMN2CYP1A1 | |
| SCHEMBL29149073 | 0.77 | GABRP (0.70) | MEN1MAPTKMT2ASMN1; SMN2CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | claimed |
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |