SCHEMBL4783697

SCHEMBL4783697

O=c1cc(-c2ccccc2)oc2c(O)ccc(O)c12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.67
MAPT P10636 5/20 0.67
CYP1A1 P04798 5/20 0.67
CYP1A2 P05177 5/20 0.67
CYP1B1 Q16678 5/20 0.67
MEN1 O00255 4/20 0.67
CYP3A4 P08684 4/20 0.67
KMT2A Q03164 4/20 0.67
SMN1; SMN2 Q16637 4/20 0.67
ALOX15 P16050 3/20 0.67
FTO Q9C0B1 3/20 0.67
PKM P14618 2/20 0.67
AR P10275 1/20 0.67
GABRP O00591 4/20 0.63
GABRD O14764 4/20 0.63
GABRA1 P14867 4/20 0.63
GABRB1 P18505 4/20 0.63
GABRG2 P18507 4/20 0.63
GABRB3 P28472 4/20 0.63
GABRA5 P31644 4/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8934562 0.88 MEN1 (0.67) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
SCHEMBL23299597 0.87 CDK5 (0.72) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
SCHEMBL30738943 0.84 ACHE (0.73) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
Norwogonin SCHEMBL760431 0.84 GABRP (0.68) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
Norwogonin SCHEMBL30485998 0.84 GABRP (0.68) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
SCHEMBL12835534 0.83 ABCB1 (0.55) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
SCHEMBL29149073 0.81 GABRP (0.70) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
SCHEMBL28066043 0.81 GABRP (0.65) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
5-Hydroxyflavone SCHEMBL2390993 0.80 AR (1.00) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1
5-Hydroxyflavone SCHEMBL30630415 0.80 AR (1.00) ALDH1A1MAPTCYP1A1CYP1A2CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 EP claimed
US-20250367305-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) 2025-12-04 US claimed
CN-120005740-A Recombinant microorganism for high-level synthesis of polyphenol compounds and application thereof 中国科学院天津工业生物技术研究所 2025-05-16 CN claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 WO claimed
US-20250011393-A1 FLAVONOID-COLLAGEN CROSSLINKED ANTIOXIDANT HYDROGEL NORTH CAROLINA STATE UNIVERSITY 2025-01-09 US claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 WO claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
WO-2024177490-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME 서울대학교산학협력단 2024-08-29 WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
US-8530426-B2 Topical use of a UGT inducer-containing composition comprising a dermatologically acceptable carrier to protect and/or enhance the state of the skin/hair and prevent and/or treat imperfections of the skin; flavanoids such as chrysin stimulates isoforms; protective coatings aging/ wrinkling resistance SEDERMA SAS (FR) 2013-09-10 US claimed
US-5650433-A REDUCING ARTICULAR CARTILAGE DESTRUCTION IN A PATIENT BY ADMINISTERING A FLAVONOID COMPOUND KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1997-07-22 US claimed
EP-0633022-B1 Chondroprotective flavones KUREHA CHEMICAL IND CO LTD (JP) 1997-02-19 EP claimed
WO-1996031206-A2 FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1996-10-10 WO claimed
EP-0496349-B1 Coating solution for preventing adhesion of polymer scale and method for its use SHINETSU CHEMICAL CO (JP) 1996-04-10 EP claimed
CN-1100633-A Chondroprotective agents KUREHA CHEMICAL IND CO LTD (JP) 1995-03-29 CN claimed
EP-0633022-A2 Chondroprotective flavones KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-01-11 EP claimed
EP-0496349-A1 Coating solution for preventing adhesion of polymer scale and method for its use SHIN-ETSU CHEMICAL CO., LTD. (JP) 1992-07-29 EP claimed
US-4617293-A Flavonoid phosphate salts of aminoglycoside antibiotics MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1986-10-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB ALDH1A1 2722/4885MAPT 3926/4885CYP1A1 3564/4885
US-20250367305-A1 ALBUMIN NANOCOMPOSITE COMPRISING PHYTOCHEMICAL AND COMPOSITION FOR IMPROVING MUSCLE DISEASE CONTAINING SAME ALB, TNNC1, MYOF ALDH1A1 2635/4885MAPT 629/4885CYP1A1 3366/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.