Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.63 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.62 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934588 | 0.91 | KDM4E (0.61) | ABCB1ABCG2KDM4EALDH1A1TP53 | |
| SCHEMBL8934603 | 0.89 | MAPT (0.78) | ABCB1ABCG2KDM4EALDH1A1TP53 | |
| SCHEMBL8934487 | 0.89 | ALDH1A1 (0.76) | ABCB1ABCG2KDM4EALDH1A1TP53 | |
| SCHEMBL3825575 | 0.82 | AR (0.80) | ABCB1ABCG2KDM4EALDH1A1TP53 | |
| SCHEMBL10632007 | 0.79 | KDM4E (0.72) | ABCB1ABCG2KDM4EALDH1A1TP53 | |
| SCHEMBL25204150 | 0.79 | KDM4E (0.73) | ABCB1KDM4EALDH1A1TP53CYP3A4 | |
| 6-Methoxyflavone SCHEMBL312059 | 0.78 | ABCB1 (1.00) | ABCB1ABCG2KDM4EALDH1A1TP53 | |
| 6-Methoxyflavone SCHEMBL28930176 | 0.78 | ABCB1 (1.00) | ABCB1ABCG2KDM4EALDH1A1TP53 | |
| 6-Methoxyflavone SCHEMBL30799564 | 0.78 | ABCB1 (1.00) | ABCB1ABCG2KDM4EALDH1A1TP53 | |
| 6,4'-Dimethoxyflavone SCHEMBL4281291 | 0.78 | MAPT (1.00) | ABCB1ABCG2KDM4EALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031206-A2 | FLAVONES AND COUMARINS AS AGENTS FOR THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-10-10 | — | — | WO | disclosed |