Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7960977 | 0.86 | NPC1 (0.43) | EPHX2NPC1RAB9A | |
| SCHEMBL7971223 | 0.85 | MEN1 (0.52) | MEN1NPC1KMT2ARAB9A | |
| SCHEMBL7973065 | 0.82 | NPC1 (0.49) | NPC1RAB9A | |
| SCHEMBL7972926 | 0.82 | PKM (0.46) | NPC1RAB9ALMNA | |
| SCHEMBL7974587 | 0.82 | NPC1 (0.46) | NPC1TSHRRAB9A | |
| SCHEMBL7961372 | 0.82 | NPC1 (0.62) | MEN1NPC1KMT2ATSHRRAB9A | |
| SCHEMBL7994461 | 0.81 | RAB9A (0.47) | NPC1RAB9ALMNA | |
| SCHEMBL8795678 | 0.80 | SLC13A3 (0.49) | NPC1RAB9ALMNA | |
| SCHEMBL7971497 | 0.78 | MAPT (0.46) | EPHX2MEN1NPC1KMT2ARAB9A | |
| SCHEMBL8686305 | 0.77 | HRH3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |