Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972926 | 0.88 | PKM (0.46) | RAB9ANPC1SMN1; SMN2CASP1HPGD | |
| SCHEMBL4387581 | 0.87 | RAB9A (0.63) | RAB9ANPC1SMN1; SMN2HPGDLMNA | |
| SCHEMBL7974587 | 0.85 | NPC1 (0.46) | RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL7973065 | 0.85 | NPC1 (0.49) | RAB9ANPC1SMN1; SMN2HPGDRECQL | |
| SCHEMBL7971223 | 0.85 | MEN1 (0.52) | RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL7961372 | 0.85 | NPC1 (0.62) | RAB9ANPC1SMN1; SMN2LMNARECQL | |
| SCHEMBL7960977 | 0.82 | NPC1 (0.43) | RAB9ANPC1SMN1; SMN2RECQL | |
| SCHEMBL4376187 | 0.82 | L3MBTL1 (0.59) | SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL8934796 | 0.81 | EPHX2 (0.46) | RAB9ANPC1LMNA | |
| Oxalic Acid SCHEMBL7994699 | 0.77 | CHEK1 (0.37) | RAB9ANPC1SMN1; SMN2ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248765-B1 | ANTIINFLAMMATORY AGENTS; HYPOTENSIVE AGENTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICAL (FR) | 2001-06-19 | — | — | US | disclosed |
| EP-0760811-A1 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H 3? (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1997-03-12 | — | — | EP | disclosed |
| WO-1996029315-A2 | IMIDAZOLE DERIVATIVES AS HISTAMINE RECEPTOR H3 (ANT)AGONISTS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (FR) | 1996-09-26 | — | — | WO | disclosed |