Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687878 | 0.87 | TSHR (0.79) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL11713193 | 0.83 | ALDH1A1 (0.66) | TSHRALDH1A1MEN1KMT2AFFAR1 | |
| SCHEMBL3649965 | 0.82 | TSHR (0.61) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL9431007 | 0.82 | EPHX2 (0.46) | TSHRCA12CA1CA2CA9 | |
| Fenuron SCHEMBL9451054 | 0.81 | TSHR (0.64) | TSHRCA12CA1CA2CA9 | |
| Fenuron SCHEMBL62004 | 0.81 | TSHR (0.64) | TSHRCA12CA1CA2CA9 | |
| Fenuron SCHEMBL8366971 | 0.81 | TSHR (0.64) | TSHRCA12CA1CA2CA9 | |
| Fenuron SCHEMBL10806698 | 0.81 | TSHR (0.64) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8887134 | 0.81 | MEN1 (0.64) | TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7821470 | 0.80 | SLC1A3 (0.47) | TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996030329-A1 | SUBSTITUTED BENZENE DERIVATIVES USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INCORPORATED (US) | 1996-10-03 | — | — | WO | disclosed |