⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9298655 | 0.77 | — | — | |
| SCHEMBL948260 | 0.77 | — | — | |
| SCHEMBL8392647 | 0.76 | KMT2A (0.40) | — | |
| SCHEMBL9669855 | 0.73 | — | — | |
| SCHEMBL6496460 | 0.73 | — | — | |
| SCHEMBL5582099 | 0.73 | — | — | |
| SCHEMBL27536763 | 0.73 | — | — | |
| SCHEMBL17429531 | 0.72 | ALDH1A1 (0.37) | — | |
| SCHEMBL9850045 | 0.72 | ALOX5 (0.40) | — | |
| SCHEMBL7098541 | 0.72 | TP53 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8213168-A | — | — | None | — | — | JP | disclosed |
| US-9475771-B2 | Process for the preparation of 4-alkoxy-3-hydroxypicolinic acids | DOW AGROSCIENCES LLC (US) | 2016-10-25 | — | — | US | disclosed |
| US-7767812-B2 | Crystals of pyrimidine compound and process for producing the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-08-03 | — | — | US | disclosed |
| US-7538117-B2 | Crystalline and amorphous pyrimidine compounds and processes for preparing pyrimidine compounds | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-05-26 | — | — | US | disclosed |
| US-20090111986-A1 | NOVEL CRYSTALS OF PYRIMIDINE COMPOUND AND PROCESS FOR PRODUCING THE SAME | HARADA HITOSHI | 2009-04-30 | — | — | US | disclosed |
| US-20070078151-A1 | Crystalline and amorphous pyrimidine compounds and processes for preparing pyrimidine compounds | EISAI CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| JP-H08213168-A | MANUFACTURE OF ELECTROLUMINESCENT ELEMENT | ALPS ELECTRIC CO LTD | 1996-08-20 | — | — | JP | disclosed |