⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935129 | 0.77 | — | — | |
| SCHEMBL948260 | 0.77 | — | — | |
| SCHEMBL919847 | 0.73 | — | — | |
| SCHEMBL7098541 | 0.72 | TP53 (0.46) | — | |
| SCHEMBL80874 | 0.72 | — | — | |
| SCHEMBL12779618 | 0.69 | ALOX5 (0.42) | — | |
| SCHEMBL467448 | 0.69 | — | — | |
| SCHEMBL141900 | 0.69 | — | — | |
| SCHEMBL4088167 | 0.69 | — | — | |
| SCHEMBL942463 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371097-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| US-5364871-A | Antiulcer agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-11-15 | — | — | US | disclosed |
| EP-0575614-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-12-29 | — | — | EP | disclosed |
| WO-1993024485-A1 | OXAZOLE DERIVATIVES AND THEIR USE AS ANTIULCER AGENTS AND H2-RECEPTOR ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-12-09 | — | — | WO | disclosed |
| WO-1992016526-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-01 | — | — | WO | disclosed |
| EP-0417751-A2 | New thiazole derivatives, processes for the preparation thereof and pharmaceutical compositon comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |