Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.67 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.60 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8389369 | 0.88 | NPC1 (0.71) | BCHEHPGDKMT2AADAMTS5GID4 | |
| SCHEMBL13652546 | 0.87 | LMNA (0.61) | BCHEHPGDKMT2AADAMTS5GID4 | |
| SCHEMBL7350528 | 0.86 | ALDH1A1 (0.63) | BCHEHPGDKMT2AADAMTS5GID4 | |
| SCHEMBL26633561 | 0.86 | BCHE (0.67) | BCHEKMT2AADAMTS5 | |
| SCHEMBL8575115 | 0.85 | LTA4H (0.63) | LTA4HBCHE | |
| SCHEMBL417953 | 0.85 | AOC3 (0.72) | HPGDKMT2ATSHRRECQLALDH1A1 | |
| SCHEMBL10133176 | 0.85 | NPC1 (0.67) | BCHEHPGDKMT2AADAMTS5GID4 | |
| Iodomethane SCHEMBL8387414 | 0.84 | NPC1 (0.70) | BCHEHPGDKMT2AADAMTS5GID4 | |
| SCHEMBL8935243 | 0.84 | GID4 (0.74) | KMT2AGID4ALDH1A1MAOB | |
| Bromide SCHEMBL10352605 | 0.84 | AOC3 (0.70) | HPGDKMT2ATSHRRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |
| CN-1027588-C | Process for the preparation of N-phenylalkyl substituted alpha-aminocarboxamide derivatives | ERBA CARLO SPA (IT) | 1995-02-08 | — | — | CN | disclosed |
| CN-1047496-A | The preparation method of the alpha-amino group Carboxylamide derivatives that N-benzene alkyl replaces | ERBA CARLO SPA (IT) | 1990-12-05 | — | — | CN | disclosed |