Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.64 |
| ▸ | RXRB | P28702 | 1/20 | 0.64 |
| ▸ | RXRG | P48443 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 7/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.56 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.55 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398313 | 0.90 | MAOB (0.62) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL7438788 | 0.89 | MAOB (0.69) | RXRARXRBRXRGMAOBMAOA | |
| Hydrochloric Acid SCHEMBL8935265 | 0.89 | MAOB (0.63) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL11663438 | 0.86 | RXRA (0.65) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL8935250 | 0.85 | MAOB (0.63) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL8935267 | 0.85 | MAOB (0.60) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL22852425 | 0.85 | NR4A2 (0.61) | MAOBMAOANR4A2GPR34 | |
| SCHEMBL515522 | 0.85 | SLC7A5 (0.69) | MAOB | |
| SCHEMBL288912 | 0.85 | SLC7A5 (0.69) | MAOB | |
| SCHEMBL659105 | 0.85 | SLC7A5 (0.69) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |