SCHEMBL22852425

SCHEMBL22852425

N[C@@H](Cc1ccc(OCc2ccc(Cl)cc2)cc1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NR4A2 P43354 1/20 0.61
MAOB P27338 6/20 0.60
MAOA P21397 1/20 0.60
ITGB3 P05106 1/20 0.58
ITGA2B P08514 1/20 0.58
SLC7A5 Q01650 2/20 0.57
GPR34 Q9UPC5 1/20 0.54
PPARA Q07869 3/20 0.54
PPARG P37231 2/20 0.54
PTPN1 P18031 1/20 0.52
ALPI P09923 1/20 0.51
PKM P14618 1/20 0.51
PTGS1 P23219 1/20 0.51
XIAP P98170 1/20 0.51
APP P05067 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515522 0.88 SLC7A5 (0.69) MAOBITGB3ITGA2BSLC7A5PPARA
SCHEMBL288912 0.88 SLC7A5 (0.69) MAOBITGB3ITGA2BSLC7A5PPARA
SCHEMBL659105 0.88 SLC7A5 (0.69) MAOBITGB3ITGA2BSLC7A5PPARA
Hydrochloric Acid SCHEMBL16816702 0.87 SLC7A5 (0.67) MAOBITGB3ITGA2BSLC7A5PPARA
SCHEMBL6065556 0.87 SLC7A5 (0.67) MAOBITGB3ITGA2BSLC7A5PPARA
SCHEMBL4757532 0.87 SLC7A5 (0.67) MAOBITGB3ITGA2BSLC7A5PPARA
Hydrochloric Acid SCHEMBL16816706 0.87 SLC7A5 (0.67) MAOBITGB3ITGA2BSLC7A5PPARA
SCHEMBL2293387 0.86 PPARG (0.61) ITGB3ITGA2BSLC7A5PPARAPPARG
SCHEMBL2293395 0.86 PPARG (0.61) ITGB3ITGA2BSLC7A5PPARAPPARG
Fenclonine SCHEMBL245828 0.86 SLC7A5 (0.69) SLC7A5PPARAPPARGPTPN1ALPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240216529-A1 EXTRACELLULAR VESICLES WITH TARGETING MOIETY BIORCHESTRA CO., LTD. (KR) 2024-07-04 US disclosed
WO-2024009268-A1 MICELLAR NANOPARTICLES AND USES THEREOF BIORCHESTRA CO., LTD. (KR) 2024-01-11 WO disclosed
US-11839624-B2 Micellar nanoparticles and uses thereof BIORCHESTRA CO., LTD. (KR) 2023-12-12 US disclosed
US-11839624-B2 Micellar nanoparticles and uses thereof BIORCHESTRA CO., LTD. (KR) 2023-12-12 US disclosed
WO-2022144811-A1 MICELLAR NANOPARTICLES AND USES THEREOF BIORCHESTRA CO., LTD. (KR) 2022-07-07 WO disclosed
WO-2020261227-A1 MICELLAR NANOPARTICLES AND USES THEREOF BIORCHESTRA CO., LTD. (KR) 2020-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240216529-A1 EXTRACELLULAR VESICLES WITH TARGETING MOIETY EXOSC5, EXOSC4, EXOSC10 NR4A2 3300/4885MAOB 3883/4885MAOA 4128/4885
US-11839624-B2 Micellar nanoparticles and uses thereof TLR9, HNRNPLL, POLRMT NR4A2 3043/4885MAOB 4696/4885MAOA 4330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.