Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 3/20 | 0.60 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | RXRG | P48443 | 1/20 | 0.55 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7398313 | 0.85 | MAOB (0.62) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL8935283 | 0.85 | RXRA (0.64) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL27312933 | 0.85 | MAOB (0.60) | MAOBALOX5FFAR1 | |
| SCHEMBL12556150 | 0.85 | PNMT (0.58) | MAOBALOX5MAOA | |
| Hydrochloric Acid SCHEMBL8935265 | 0.84 | MAOB (0.63) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL8935267 | 0.84 | MAOB (0.60) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL8935296 | 0.82 | ALOX5 (0.60) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL8935307 | 0.82 | ALOX5 (0.60) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL8935317 | 0.81 | ALOX5 (0.62) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL11212089 | 0.81 | MAOB (0.70) | MAOBALOX5MAOARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |