Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 2/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465420 | 0.96 | SMN1; SMN2 (0.33) | SMN1; SMN2HIF1AALDH1A1GAANPY1R | |
| SCHEMBL7466587 | 0.82 | CCR4 (0.36) | SMN1; SMN2HIF1AALDH1A1GAANPY1R | |
| SCHEMBL7467654 | 0.82 | NPY1R (0.37) | SMN1; SMN2HIF1AALDH1A1GAANPY1R | |
| SCHEMBL7468793 | 0.81 | CCR4 (0.36) | SMN1; SMN2HIF1AALDH1A1GAANPY1R | |
| SCHEMBL7470948 | 0.81 | GLP1R (0.33) | SMN1; SMN2HIF1AALDH1A1GAANPY1R | |
| SCHEMBL7475650 | 0.78 | CCR4 (0.35) | CCR4KDM4EMAPTPIK3CA | |
| SCHEMBL7476942 | 0.76 | ALDH1A1 (0.38) | SMN1; SMN2HIF1AALDH1A1GAANPY1R | |
| SCHEMBL7462801 | 0.75 | CCR4 (0.36) | SMN1; SMN2HIF1ACCR4BRAFLMNA | |
| SCHEMBL8935248 | 0.75 | PIK3CA (0.32) | PIK3CA | |
| SCHEMBL7468982 | 0.73 | ALDH1A1 (0.45) | SMN1; SMN2HIF1AALDH1A1GAANPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996009295-A1 | QUINOXALINE DERIVATIVES USEFUL IN THERAPY | PFIZER LIMITED (GB) | 1996-03-28 | — | — | WO | disclosed |