Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27322135 | 0.94 | ADAMTS4 (0.48) | MMP13ACACBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL28505503 | 0.89 | RAB9A (0.51) | MMP13RAB9ASMN1; SMN2MAPK1NPC1 | |
| SCHEMBL8935338 | 0.85 | PARP10 (0.48) | MMP13MMP2MMP1MMP9 | |
| SCHEMBL27309675 | 0.84 | PARP10 (0.57) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL28497294 | 0.83 | SIRT2 (0.47) | RAB9AMAPTGPR132 | |
| Hydrochloric Acid SCHEMBL27353104 | 0.83 | PARP10 (0.56) | RAB9ASMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL28503302 | 0.83 | PARP10 (0.45) | MMP13RAB9AALDH1A1MAPTMMP2 | |
| SCHEMBL27311683 | 0.80 | PPARG (0.53) | SMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL27344680 | 0.80 | MMP13 (0.44) | MMP13MMP2 | |
| SCHEMBL28904310 | 0.79 | NPC1 (0.56) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |