Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935256 | 0.80 | POLB (0.59) | ALDH1A1TSHRHPGDLMNAPOLB | |
| SCHEMBL8935330 | 0.80 | EPHX2 (0.57) | ALDH1A1TSHRRECQLTPSAB1LMNA | |
| SCHEMBL8935386 | 0.79 | CARM1 (0.51) | LTA4HKMT2AMEN1PARP15PARP10 | |
| SCHEMBL8935259 | 0.77 | CYP3A4 (0.60) | ALDH1A1TSHRRECQLLMNACYP2C19 | |
| SCHEMBL8935236 | 0.77 | MAOB (0.63) | PARP10 | |
| SCHEMBL8935322 | 0.77 | GID4 (0.71) | ALDH1A1POLBCYP2C19HTTGID4 | |
| SCHEMBL8935432 | 0.76 | SCN3A (0.66) | ALDH1A1TSHRRECQLLMNAKMT2A | |
| SCHEMBL8935279 | 0.75 | MAOB (0.60) | ALDH1A1TSHRRECQLLMNAPOLB | |
| SCHEMBL8935404 | 0.75 | PARP10 (0.56) | ALDH1A1TSHRRECQLHPGDLMNA | |
| SCHEMBL12351779 | 0.75 | MAOB (0.56) | HPGDLTA4HPARP15PARP10PARP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |