Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935264 | 0.81 | RAB9A (0.54) | POLBRAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL8935382 | 0.80 | ALDH1A1 (0.46) | POLBRAB9ANPC1HPGDMEN1 | |
| SCHEMBL8935330 | 0.80 | EPHX2 (0.57) | RAB9ANPC1SMN1; SMN2TSHRMAPK1 | |
| SCHEMBL1680389 | 0.76 | MAOB (0.54) | POLBHPGD | |
| SCHEMBL8935432 | 0.76 | SCN3A (0.66) | RAB9ANPC1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7397015 | 0.76 | SCN9A (0.61) | POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL4816702 | 0.76 | SCN9A (0.61) | POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL8935279 | 0.75 | MAOB (0.60) | POLBSMN1; SMN2MEN1KMT2ATSHR | |
| SCHEMBL8935404 | 0.75 | PARP10 (0.56) | POLBRAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL3497972 | 0.74 | POLB (0.53) | POLBRAB9ANPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |