Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | EPOR | P19235 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416662 | 0.86 | NPC1 (0.60) | RAB9AALOX5NPC1SMN1; SMN2PTGS1 | |
| SCHEMBL8652025 | 0.86 | ALOX5 (0.76) | RAB9AALOX5NPC1SMN1; SMN2PTGS1 | |
| SCHEMBL6418344 | 0.83 | ALOX5 (0.74) | RAB9AALOX5NPC1SMN1; SMN2PTGS1 | |
| SCHEMBL7397152 | 0.83 | NPC1 (0.72) | RAB9ANPC1SMN1; SMN2MAPK1KMT2A | |
| SCHEMBL414702 | 0.78 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2MAPK1LTB4R | |
| SCHEMBL11364330 | 0.78 | AOC3 (0.77) | — | |
| SCHEMBL7402193 | 0.77 | LTA4H (0.64) | ALOX5PTGS1PTGS2L3MBTL1LTB4R | |
| SCHEMBL8494501 | 0.77 | ALOX5 (0.61) | RAB9AALOX5NPC1SMN1; SMN2PTGS1 | |
| SCHEMBL8826002 | 0.77 | ALOX5 (0.61) | RAB9AALOX5NPC1SMN1; SMN2PTGS1 | |
| SCHEMBL4798737 | 0.77 | ALOX5 (0.58) | RAB9AALOX5NPC1SMN1; SMN2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502079-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1996-03-26 | — | — | US | disclosed |