Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | CACNB4 | O00305 | 2/20 | 0.33 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.33 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.33 |
| ▸ | CACNG3 | O60359 | 2/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770592 | 0.94 | L3MBTL1 (0.42) | KDRADORA2ALMNAHCRTR1HCRTR2 | |
| SCHEMBL7717266 | 0.88 | ADORA2A (0.37) | MEN1KMT2AADORA2ALMNAHCRTR1 | |
| SCHEMBL30803820 | 0.88 | ADORA2A (0.37) | MEN1KMT2AADORA2ALMNAHCRTR1 | |
| SCHEMBL8936038 | 0.87 | ADORA2A (0.37) | MEN1KMT2AADORA2ALMNAHCRTR1 | |
| SCHEMBL8935948 | 0.86 | ADORA2A (0.36) | MEN1KMT2AADORA2ALMNAHCRTR1 | |
| SCHEMBL8755383 | 0.86 | ALDH1A1 (0.40) | MEN1KMT2ALMNAALDH1A1CYP1A2 | |
| SCHEMBL8935801 | 0.85 | ALDH1A1 (0.42) | MEN1KMT2ALMNAHTTALDH1A1 | |
| SCHEMBL8935762 | 0.85 | KMT2A (0.43) | MEN1KMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL8755637 | 0.85 | SMN1; SMN2 (0.45) | MEN1KMT2AALDH1A1L3MBTL1PIM1 | |
| SCHEMBL8547909 | 0.83 | KDR (0.37) | KDRMEN1KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539117-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | GE HEALTHCARE AS (NO) | 1996-07-23 | — | — | US | disclosed |
| US-5350696-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | STERLING WINTHROP, INC. (US) | 1994-09-27 | — | — | US | disclosed |