Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7770566 | 0.94 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2PDGFRBPDGFRAMAPT | |
| SCHEMBL8935970 | 0.89 | GRK6 (0.45) | ALDH1A1SMN1; SMN2PDGFRBPDGFRAMAPT | |
| SCHEMBL8935763 | 0.85 | KDR (0.37) | ALDH1A1HTTMEN1KMT2AHPGD | |
| SCHEMBL8548153 | 0.84 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2PDGFRBPDGFRAMAPT | |
| SCHEMBL8935762 | 0.82 | KMT2A (0.43) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7770592 | 0.80 | L3MBTL1 (0.42) | ALDH1A1HTTHPGDLMNAKDM4E | |
| SCHEMBL8755383 | 0.79 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL14008666 | 0.78 | NR1D1 (0.38) | ALDH1A1SMN1; SMN2MAPTHTTRAB9A | |
| SCHEMBL8755637 | 0.78 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL7770589 | 0.76 | PPARG (0.41) | ALDH1A1MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539117-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | GE HEALTHCARE AS (NO) | 1996-07-23 | — | — | US | disclosed |
| US-5350696-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | STERLING WINTHROP, INC. (US) | 1994-09-27 | — | — | US | disclosed |