Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | GYS1 | P13807 | 1/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717266 | 0.98 | ADORA2A (0.37) | ADORA2AGYS1SLC6A9ALDH1A1LMNA | |
| SCHEMBL30803820 | 0.98 | ADORA2A (0.37) | ADORA2AGYS1SLC6A9ALDH1A1LMNA | |
| SCHEMBL8936038 | 0.97 | ADORA2A (0.37) | ADORA2AGYS1SLC6A9ALDH1A1LMNA | |
| SCHEMBL7770333 | 0.92 | ADORA2A (0.44) | ADORA2ASLC6A9ALDH1A1ADORA3KDM4E | |
| SCHEMBL8935770 | 0.90 | ALDH1A1 (0.42) | ADORA2AGYS1SLC6A9ALDH1A1ADORA3 | |
| SCHEMBL8601997 | 0.89 | ALDH1A1 (0.44) | GYS1SLC6A9ALDH1A1LMNAHTT | |
| SCHEMBL8935763 | 0.86 | KDR (0.37) | ADORA2AALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL7774104 | 0.83 | ADORA2A (0.43) | ADORA2AALDH1A1ADORA3KDM4EHCRTR1 | |
| SCHEMBL8935970 | 0.82 | GRK6 (0.45) | ALDH1A1LMNAHTTL3MBTL1KDM4E | |
| SCHEMBL663382 | 0.82 | SLC6A9 (0.36) | SLC6A9ALDH1A1LMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5539117-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | GE HEALTHCARE AS (NO) | 1996-07-23 | — | — | US | disclosed |
| US-5350696-A | 2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines | STERLING WINTHROP, INC. (US) | 1994-09-27 | — | — | US | disclosed |