Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533566 | 0.89 | PKM (0.51) | PKMPPARASMN1; SMN2PPARGMAPT | |
| SCHEMBL27971306 | 0.85 | SMN1; SMN2 (0.51) | PPARASMN1; SMN2PPARGMAPTPTGDR2 | |
| SCHEMBL8935780 | 0.85 | PPARA (0.52) | PKMPPARASMN1; SMN2PPARGMAPT | |
| SCHEMBL8935782 | 0.85 | PPARA (0.52) | PKMPPARASMN1; SMN2PPARGMAPT | |
| SCHEMBL11364459 | 0.82 | PPARA (0.50) | PPARASMN1; SMN2PPARGPTGDR2RAB9A | |
| SCHEMBL1245341 | 0.81 | PPARA (0.49) | PPARASMN1; SMN2PPARGMAPTRAB9A | |
| SCHEMBL8935797 | 0.81 | PPARA (0.49) | PPARASMN1; SMN2PPARGMAPTRAB9A | |
| SCHEMBL6780384 | 0.81 | SMN1; SMN2 (0.46) | PKMPPARASMN1; SMN2PPARGMAPT | |
| SCHEMBL5861916 | 0.81 | SMN1; SMN2 (0.59) | PPARASMN1; SMN2PPARGMAPTPTGDR2 | |
| Hydrochloric Acid SCHEMBL8074407 | 0.80 | PPARA (0.48) | PPARASMN1; SMN2PPARGMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163727-B2 | Biphenyloxyacetic acid derivatives for the treatment of respiratory disease | ASTRAZENECA AB (SE) | 2012-04-24 | — | — | US | disclosed |