SCHEMBL8935886

SCHEMBL8935886

O=[N+]([O-])c1ccc([C@@]2(O)[C@@H](O)C(O)O[C@H](CO)[C@@H]2O)cc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
LGALS3 P17931 1/20 0.41
HK1 P19367 1/20 0.41
HK2 P52789 1/20 0.41
CYP1A2 P05177 1/20 0.39
NFKB1 P19838 1/20 0.39
THPO P40225 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PMP22 Q01453 1/20 0.39
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
GBA1 P04062 1/20 0.35
MANBA O00462 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4319795 0.79 LGALS3 (0.46) TSHRLGALS3HK1HK2CYP1A2
SCHEMBL27775834 0.79 LGALS3 (0.40) TSHRLGALS3HK1HK2CYP1A2
SCHEMBL18863897 0.77 PTGS2 (0.40) HK1HK2
SCHEMBL14939237 0.77 PTGS2 (0.40) HK1HK2
SCHEMBL3494618 0.74 LGALS3 (0.41) TSHRLGALS3CYP1A2NFKB1THPO
P-Nitrophenol SCHEMBL344882 0.74 HK1 (0.51) LGALS3HK1HK2CYP1A2NFKB1
SCHEMBL1935137 0.73 CYP1A2 (0.41) TSHRLGALS3HK1HK2CYP1A2
SCHEMBL10877634 0.73 CYP1A2 (0.41) TSHRLGALS3HK1HK2CYP1A2
SCHEMBL10871363 0.73 CYP1A2 (0.41) TSHRLGALS3HK1HK2CYP1A2
B-D-Galactose SCHEMBL7519216 0.72 HK1 (0.50) LGALS3HK1HK2CYP1A2NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0654087-A4 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS. SCRIPPS RESEARCH INST (US) 1996-12-18 EP disclosed
EP-0654087-A1 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS THE SCRIPPS RESEARCH INSTITUTE (US) 1995-05-24 EP disclosed
WO-1994002624-A1 A FACILE ENZYMATIC SYNTHESIS OF GALACTOSYL-BETA-1,3 GLYCALS THE SCRIPPS RESEARCH INSTITUTE (US) 1994-02-03 WO disclosed