Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.55 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9769601 | 0.93 | ALDH1A1 (0.54) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR | |
| SCHEMBL8448326 | 0.86 | HCAR3 (0.55) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR | |
| SCHEMBL9769611 | 0.84 | HCAR3 (0.53) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR | |
| SCHEMBL27727791 | 0.81 | HCAR3 (0.48) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR | |
| SCHEMBL9985764 | 0.79 | VCAM1 (0.51) | HCAR3ALDH3A1ALDH1A1KDM4EMEN1 | |
| SCHEMBL7041286 | 0.79 | TSHR (0.53) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR | |
| SCHEMBL11880900 | 0.78 | TSHR (0.51) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR | |
| SCHEMBL16176930 | 0.77 | ALDH1A1 (0.51) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR | |
| SCHEMBL8331988 | 0.77 | ALDH3A1 (0.49) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR | |
| SCHEMBL7809597 | 0.76 | ALDH1A1 (0.52) | HCAR3ALDH3A1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | claimed |
| EP-0182330-A2 | Use of 2-nitroaniline derivatives as hair dyeing agents, and 2-nitroaniline derivatives | Wella Aktiengesellschaft (DE) | 1986-05-28 | — | — | EP | claimed |
| JP-8269348-A | — | — | None | — | — | JP | disclosed |
| JP-H08269348-A | NOVEL 2-NITROANILINE DERIVATIVE | WELLA AG | 1996-10-15 | — | — | JP | disclosed |
| US-5037446-A | 2-nitroaniline derivatives and hair dyeing compositions containing same | WELLA AKTIENGESELLSCHAFT (DE) | 1991-08-06 | — | — | US | disclosed |
| EP-0182330-B1 | USE OF 2-NITROANILINE DERIVATIVES AS HAIR DYEING AGENTS, AND 2-NITROANILINE DERIVATIVES | Wella Aktiengesellschaft (DE) | 1991-05-15 | — | — | EP | disclosed |
| US-4835314-A | 2-nitroaniline derivatives | WELLA AKTIENGESELLSCHAFT (DE) | 1989-05-30 | — | — | US | disclosed |