Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29280769 | 0.84 | MEN1 (0.34) | HSD11B1NR1H2ATMPTPN1 | |
| SCHEMBL19074545 | 0.84 | MEN1 (0.34) | HSD11B1NR1H2ATMPTPN1 | |
| SCHEMBL9696891 | 0.84 | MEN1 (0.34) | HSD11B1NR1H2ATMPTPN1 | |
| SCHEMBL18700390 | 0.82 | ELANE (0.36) | ATM | |
| SCHEMBL12300133 | 0.82 | HSD11B1 (0.34) | HSD11B1NR1H2ATMPTPN1 | |
| SCHEMBL17930909 | 0.81 | ALDH1A1 (0.34) | HSD11B1NR1H2ATM | |
| SCHEMBL25569896 | 0.81 | ATM (0.37) | HSD11B1NR1H2ATM | |
| SCHEMBL8936130 | 0.81 | NR1H2 (0.42) | HSD11B1NR1H2ATM | |
| SCHEMBL585407 | 0.81 | MEN1 (0.33) | HSD11B1NR1H2ATM | |
| SCHEMBL585406 | 0.81 | MEN1 (0.33) | HSD11B1NR1H2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659178-A4 | CHIRAL QUINOLONE INTERMEDIATES. | ABBOTT LAB (US) | 1996-03-27 | — | — | EP | disclosed |
| EP-0659178-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994006766-A1 | CHIRAL QUINOLONE INTERMEDIATES | ABBOTT LABORATORIES (US) | 1994-03-31 | — | — | WO | disclosed |
| US-5252747-A | Chiral quinolone intermediates | ABBOTT LABORATORIES (US) | 1993-10-12 | — | — | US | disclosed |