Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935987 | 0.84 | GAA (0.33) | SMN1; SMN2GAAALDH1A1L3MBTL1HTT | |
| SCHEMBL8936008 | 0.83 | KCNH2 (0.35) | SMN1; SMN2GAA | |
| SCHEMBL8936009 | 0.79 | GAA (0.37) | KMT2ASMN1; SMN2CYP1A2GAAALDH1A1 | |
| SCHEMBL8936020 | 0.73 | LMNA (0.34) | SMN1; SMN2GAAALDH1A1L3MBTL1HTT | |
| SCHEMBL10000161 | 0.69 | NPSR1 (0.46) | KMT2ASMN1; SMN2GAAALDH1A1L3MBTL1 | |
| SCHEMBL25745097 | 0.69 | KMT2A (0.33) | KMT2AALDH1A1HSD17B10LMNA | |
| SCHEMBL1562312 | 0.68 | TSHR (0.50) | MTNR1AMTNR1BKMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8936123 | 0.66 | TP53 (0.40) | SMN1; SMN2CYP1A2GAATSHR | |
| SCHEMBL30281258 | 0.65 | CA12 (0.45) | KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL209638 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |