Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.33 |
| ▸ | GSTM2 | P28161 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | STAT5B | P51692 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936020 | 0.85 | LMNA (0.34) | GAASMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL8935987 | 0.85 | GAA (0.33) | GAASMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL8936008 | 0.83 | KCNH2 (0.35) | GAASMN1; SMN2CA12CA1CA2 | |
| SCHEMBL10000161 | 0.81 | NPSR1 (0.46) | GAASMN1; SMN2ALDH1A1NPC1TP53 | |
| SCHEMBL8936154 | 0.79 | MTNR1A (0.38) | GAASMN1; SMN2ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL8936001 | 0.77 | SMN1; SMN2 (0.37) | SMN1; SMN2ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL30281258 | 0.76 | CA12 (0.45) | ALDH1A1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL8936066 | 0.76 | GAA (0.31) | GAACA12CA1CA2CA9 | |
| SCHEMBL8936146 | 0.72 | ALDH1A1 (0.45) | GAASMN1; SMN2ALDH1A1TP53CA12 | |
| SCHEMBL23989782 | 0.71 | HIF1A (0.50) | GAASMN1; SMN2ALDH1A1NPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |