Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936035 | 0.91 | MAP2K1 (0.32) | MAP2K1GAASMN1; SMN2 | |
| SCHEMBL8935987 | 0.89 | GAA (0.33) | GAASMN1; SMN2 | |
| SCHEMBL8936009 | 0.83 | GAA (0.37) | CA12CA1CA2CA9GAA | |
| Hydrochloric Acid SCHEMBL8936066 | 0.80 | GAA (0.31) | CA12CA1CA2CA9GAA | |
| SCHEMBL8936020 | 0.76 | LMNA (0.34) | GAASMN1; SMN2 | |
| SCHEMBL8936146 | 0.76 | ALDH1A1 (0.45) | CA12CA1CA2CA9GAA | |
| SCHEMBL30281258 | 0.75 | CA12 (0.45) | CA12CA1CA2CA9 | |
| SCHEMBL8935984 | 0.74 | SMN1; SMN2 (0.39) | GAASMN1; SMN2 | |
| SCHEMBL8936123 | 0.72 | TP53 (0.40) | GAASMN1; SMN2 | |
| SCHEMBL8936001 | 0.72 | SMN1; SMN2 (0.37) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486531-A | ANGINA, HYPOTENSIVE AGENTS, ERECTILE DYSFUNCTION | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-01-23 | — | — | US | disclosed |