Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936601 | 0.89 | TACR1 (0.70) | TACR1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8936542 | 0.84 | TACR1 (0.86) | TACR1ALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL8936576 | 0.76 | TACR1 (1.00) | TACR1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8785120 | 0.75 | TACR1 (0.45) | TACR1ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL8936577 | 0.73 | TACR1 (0.76) | TACR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8936508 | 0.72 | TACR1 (0.59) | TACR1ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL8936439 | 0.72 | TACR1 (0.86) | TACR1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL8936527 | 0.71 | TACR1 (0.90) | TACR1ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL9178393 | 0.71 | TACR1 (0.57) | TACR1KDM4ESMN1; SMN2POLBNPC1 | |
| SCHEMBL8936587 | 0.71 | TACR1 (0.64) | TACR1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523305-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0566069-A1 | Tachykinin receptor antagonists, isoquinolones and their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |