Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 5/20 | 0.51 |
| ▸ | MMP9 | P14780 | 5/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936409 | 0.83 | MMP2 (0.51) | MMP2MMP9CA2ALDH1A1MAPT | |
| SCHEMBL23049688 | 0.78 | CA2 (0.48) | MMP2MMP9CA2ALDH1A1ATM | |
| SCHEMBL23049767 | 0.78 | CA2 (0.48) | MMP2MMP9CA2ALDH1A1ATM | |
| SCHEMBL9614215 | 0.76 | MMP2 (0.60) | MMP2MMP9MEN1KMT2ACYP2C9 | |
| SCHEMBL27182592 | 0.75 | CA2 (0.46) | MMP2MMP9CA2ALDH1A1ATM | |
| SCHEMBL9614009 | 0.75 | MMP2 (0.47) | MMP2MMP9TAS2R14MMP1MMP13 | |
| SCHEMBL27911762 | 0.73 | MMP2 (0.70) | MMP2MMP9ALDH1A1KMT2ACYP2C19 | |
| SCHEMBL9570487 | 0.71 | MMP2 (0.52) | MMP2MMP9CA2ALDH1A1MAPT | |
| SCHEMBL23049886 | 0.71 | CA2 (0.48) | CA2ALDH1A1ATML3MBTL1AKR1C3 | |
| SCHEMBL7772552 | 0.71 | MMP2 (0.51) | MMP2MMP9CA2L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498798-A | 4-alkyl-3-chlorobenzenesulfinic acids, 4-alkyl-3-chlorobenzenesulfonylcarboxylic acids, 4-alkyl-3-chloroalkylsulfonylbenzenes and preparation thereof | HOECHST AG (DE) | 1996-03-12 | — | — | US | disclosed |