Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3486789 | 0.82 | TSHR (0.50) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3486787 | 0.82 | TSHR (0.50) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL11293523 | 0.81 | PDK1 (0.43) | TSHRALDH1A1NPSR1POLBHCAR3 | |
| SCHEMBL16753005 | 0.79 | MAPK1 (0.46) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3247412 | 0.78 | MAPK1 (0.43) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3199616 | 0.77 | MAPK1 (0.58) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL16752924 | 0.77 | L3MBTL1 (0.48) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3487462 | 0.74 | HCAR3 (0.51) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL29686179 | 0.74 | TSHR (0.50) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL3487466 | 0.74 | HCAR3 (0.51) | MAPK1TSHRALDH1A1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |