Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.43 |
| ▸ | FNTA | P49354 | 4/20 | 0.42 |
| ▸ | FNTB | P49356 | 4/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936722 | 0.82 | CYP19A1 (0.46) | MEN1KMT2ACYP19A1ALDH1A1SLC6A4 | |
| SCHEMBL9194951 | 0.78 | FNTA (0.56) | MEN1KMT2ACYP19A1FNTAFNTB | |
| SCHEMBL8936690 | 0.75 | MEN1 (0.47) | MEN1KMT2ACYP19A1FNTAFNTB | |
| SCHEMBL8936764 | 0.74 | NLRP3 (0.40) | MEN1KMT2ACYP19A1ALDH1A1SLC6A4 | |
| SCHEMBL9201316 | 0.74 | CYP19A1 (0.46) | CYP19A1SLC6A4CYP11B1 | |
| SCHEMBL9707231 | 0.73 | CYP11B1 (0.51) | CYP19A1ALDH1A1TBXAS1CYP2A6CYP11B1 | |
| SCHEMBL8936726 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2ACYP19A1FNTAFNTB | |
| SCHEMBL9204708 | 0.71 | CYP19A1 (0.44) | MEN1KMT2ACYP19A1ALDH1A1SLC6A4 | |
| SCHEMBL8936731 | 0.71 | NLRP3 (0.39) | CYP19A1SLC6A4CYP11B1 | |
| SCHEMBL9201287 | 0.70 | CYP19A1 (0.39) | MEN1KMT2ACYP19A1ALDH1A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |