Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 10/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9525410 | 0.83 | CYP11B1 (0.51) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL9527191 | 0.83 | CYP19A1 (0.52) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL9527239 | 0.82 | SLC9A1 (0.49) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL9527151 | 0.82 | CYP11B1 (0.50) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL9524018 | 0.80 | ALDH1A1 (0.47) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL9527653 | 0.80 | CYP19A1 (0.46) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL9523481 | 0.79 | CYP11B1 (0.52) | CYP11B1CYP19A1CYP11B2TBXAS1 | |
| SCHEMBL9524490 | 0.79 | CYP11B1 (0.60) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL9523846 | 0.78 | ALDH1A1 (0.46) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL9527175 | 0.78 | CYP19A1 (0.47) | CYP11B1CYP19A1CYP11B2CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992022536-A1 | VINYLIMIDAZOLES, VINYLTRIAZOLES AND VINYLTETRAZOLES WITH A BICYCLIC SUBSTITUENT GROUP | SCHERING AKTIENGESELLSCHAFT, BERLIN UND BERGKAMEN (DE) | 1992-12-23 | — | — | WO | disclosed |
| EP-0518457-A1 | Bicyclic substituted vinylimidazoles, -triazoles and -tetrazoles | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-12-16 | — | — | EP | disclosed |