Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ADCY8 | P40145 | 3/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | ADCY1 | Q08828 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15107929 | 0.78 | SMN1; SMN2 (0.69) | LMNAALDH1A1POLBBACE1FABP4 | |
| SCHEMBL6998274 | 0.76 | LMNA (0.47) | LMNAALDH1A1POLBBACE1FABP4 | |
| SCHEMBL2403638 | 0.76 | BACE1 (0.73) | LMNAALDH1A1POLBBACE1FABP4 | |
| SCHEMBL25350548 | 0.73 | PKM (0.68) | LMNAALDH1A1POLBSMN1; SMN2PKM | |
| Benzene SCHEMBL8508944 | 0.73 | BACE1 (0.69) | LMNAALDH1A1POLBBACE1FABP4 | |
| SCHEMBL1895087 | 0.73 | BACE1 (0.54) | LMNAALDH1A1BACE1SMN1; SMN2CYP1A2 | |
| SCHEMBL18701579 | 0.73 | LMNA (0.49) | LMNAALDH1A1POLBBACE1FABP4 | |
| SCHEMBL25346762 | 0.72 | GAA (0.61) | LMNAALDH1A1POLBBACE1FABP4 | |
| SCHEMBL1893581 | 0.71 | GPR84 (0.59) | LMNABACE1FABP4SMN1; SMN2CYP1A2 | |
| SCHEMBL8677240 | 0.69 | POLB (0.70) | POLBSMN1; SMN2PKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5567817-A | Triazole antifungal agents | PFIZER INC. (US) | 1996-10-22 | — | — | US | disclosed |