SCHEMBL260023

SCHEMBL260023

CC(=O)O[C@]1(C(C)=O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 7/20 0.74
LMNA P02545 6/20 0.74
NR3C1 P04150 6/20 0.74
CYP3A4 P08684 6/20 0.74
PGR P06401 5/20 0.74
NPSR1 Q6W5P4 4/20 0.74
HIF1A Q16665 4/20 0.74
MEN1 O00255 3/20 0.74
KMT2A Q03164 3/20 0.74
ADORA3 P0DMS8 3/20 0.74
MAPT P10636 2/20 0.74
SLC6A3 Q01959 2/20 0.74
HPGD P15428 1/20 0.74
MLNR O43193 1/20 0.74
NR1I2 O75469 1/20 0.74
HTT P42858 1/20 0.74
PDE4D Q08499 1/20 0.74
PDE3A Q14432 1/20 0.74
SHBG P04278 4/20 0.70
AR P10275 4/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27048175 1.00 SMN1; SMN2 (0.74) SMN1; SMN2LMNANR3C1CYP3A4PGR
SCHEMBL29766827 1.00 SMN1; SMN2 (0.74) SMN1; SMN2LMNANR3C1CYP3A4PGR
SCHEMBL260024 1.00 SMN1; SMN2 (0.74) SMN1; SMN2LMNANR3C1CYP3A4PGR
SCHEMBL13941349 1.00 SMN1; SMN2 (0.74) SMN1; SMN2LMNANR3C1CYP3A4PGR
SCHEMBL12666930 1.00 SMN1; SMN2 (0.74) SMN1; SMN2LMNANR3C1CYP3A4PGR
SCHEMBL8853536 0.91 LMNA (0.72) SMN1; SMN2LMNANR3C1CYP3A4PGR
SCHEMBL8937171 0.91 LMNA (0.72) SMN1; SMN2LMNANR3C1CYP3A4PGR
Medroxyprogesterone Acetate SCHEMBL10949732 0.91 NR3C1 (0.88) SMN1; SMN2LMNANR3C1CYP3A4PGR
SCHEMBL11810769 0.91 AR (0.63) SMN1; SMN2LMNANR3C1CYP3A4PGR
SCHEMBL11810794 0.91 AR (0.63) SMN1; SMN2LMNANR3C1CYP3A4PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1835 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250319100-A1 ANTI-TUMOR COMBINED PREPARATION COMPRISING HYDROXYPROGESTERONE CAPROATE AND USE THEREOF SHENZHEN EVERGREEN THERAPEUTICS CO., LTD. (CN) 2025-10-16 US claimed
US-20250195450-A1 BIOERODIBLE DRUG DELIVERY IMPLANTS HERA HEALTH SOLUTIONS INC. 2025-06-19 US claimed
CN-119173283-A Radiopharmaceutical complexes targeting prostate specific membrane antigen and combinations thereof 拜耳股份有限公司 2024-12-20 CN claimed
EP-4309658-A1 ANTI-TUMOR COMBINED PREPARATION COMPRISING HYDROXYPROGESTERONE CAPROATE AND USE THEREOF Shenzhen Evergreen Therapeutics Co., Ltd. (CN) 2024-01-24 EP claimed
CN-117285583-A Preparation method of steroid medicine modified by oxidation at 6-position or 10-position 中国科学院上海药物研究所 2023-12-26 CN claimed
US-20230181599-A1 PROGESTOGEN FORMULATIONS AND USES THEREOF SHENZHEN EVERGREEN THERAPEUTICS CO LTD (CN) 2023-06-15 US claimed
US-20220008334-A1 GASTRIC RETENTIVE DEVICES CLEXIO BIOSCIENCES LTD. (IL) 2022-01-13 US claimed
CN-110618225-B Method for constructing database to detect hormone 吉林出入境检验检疫局检验检疫技术中心 2021-11-26 CN claimed
US-20210361674-A1 Treating Auto-Immune and Auto-Inflammatory Diseases SHENZHEN EVERGREEN THERAPEUTICS CO., LTD. (CN) 2021-11-25 US claimed
WO-2021226390-A1 PROGESTOGEN FORMULATIONS AND USES THEREOF SHENZHEN EVERGREEN THERAPEUTICS CO., LTD. (CN) 2021-11-11 WO claimed
WO-2000042955-A1 DRUG DOSAGE UNIT FOR BUCCAL ADMINISTRATION OF STEROIDAL ACTIVE AGENTS PLACE VIRGIL A (US) 2000-07-27 WO claimed
WO-2000042942-A2 BUCCAL DRUG DELIVERY SYSTEM FOR USE IN MALE CONTRACEPTION PLACE VIRGIL A (US) 2000-07-27 WO claimed
US-5906830-A POLYMER, DRUG MIXTURE CYGNUS, INC. (US) 1999-05-25 US claimed
US-5902603-A INCLUDING A PERMEABILITY ENHANCER ABSORBED THEREIN; HIGHER LOADS; HIGH CAPACITY AND FLUX; CROSSLINKED POLYURETHANE REACTED WITH WATER; ADMINISTERING STEROIDS AND OLANZAPINE CYGNUS, INC. (US) 1999-05-11 US claimed
US-5023088-A Drug delivery dispenser ALZA CORPORATION (US) 1991-06-11 US claimed
US-4588529-A Mercury removal process THE UPJOHN COMPANY (US) 1986-05-13 US claimed
US-4154748-A Phosphate catalyzed acylation of steroidal tertiary alcohols THE UPJOHN COMPANY (US) 1979-05-15 US claimed
US-4016270-A Method for treating dysmenorrhea with a uterine therapeutic system ALZA CORPORATION (US) 1977-04-05 US claimed
US-4014988-A Method for treating hypermenorrhea with uterine therapeutic system ALZA CORPORATION (US) 1977-03-29 US claimed
US-3993072-A Microporous drug delivery device ALZA CORPORATION (US) 1976-11-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210361674-A1 Treating Auto-Immune and Auto-Inflammatory Diseases IL17A, IL23R, IL15 SMN1; SMN2 4443/4885LMNA 4156/4885NR3C1 6/4885
US-20230181599-A1 PROGESTOGEN FORMULATIONS AND USES THEREOF SHBG, PGR, CYP17A1 SMN1; SMN2 1289/4885LMNA 847/4885NR3C1 42/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.