SCHEMBL8937595

SCHEMBL8937595

C=CCNC(=O)Nc1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.53
MAOB P27338 1/20 0.53
GAA P10253 4/20 0.51
MAPK1 P28482 1/20 0.49
PIK3CA P42336 1/20 0.49
MTOR P42345 1/20 0.49
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
KDM4E B2RXH2 2/20 0.47
MAPT P10636 4/20 0.47
CYP1A1 P04798 2/20 0.47
PEPD P12955 1/20 0.47
MEN1 O00255 1/20 0.47
CA12 O43570 1/20 0.47
BRD4 O60885 1/20 0.47
NR1I2 O75469 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
MB P02144 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10943175 0.84 MAOA (0.45) MAOAMAOBGAAMAPK1PIK3CA
SCHEMBL6037531 0.84 NPC1 (0.62) GAAHTTMAPTMEN1ALDH1A1
SCHEMBL29050565 0.84 ALDH1A1 (0.55) MAOAMAOBGAAMAPK1LMNA
SCHEMBL1649522 0.83 EPHX1 (0.59) MAOAMAOBLMNAHTTKDM4E
SCHEMBL11152964 0.82 BAZ1A (0.52) GAAMAPK1MTORLMNAHTT
Ammonia Solution, Strong SCHEMBL11319855 0.81 EPHX1 (0.57) MAOBLMNAHTTKDM4EMAPT
SCHEMBL4745789 0.81 MAOA (0.57) MAOAMAOBGAAMAPK1MTOR
SCHEMBL21114797 0.81 GAA (0.48) GAALMNAHTTKDM4EALDH1A1
SCHEMBL6616236 0.80 RAB9A (0.66) KDM4EMAPTMEN1KMT2AL3MBTL1
SCHEMBL8868161 0.80 CNR1 (0.50) GAALMNAHTTKDM4ETHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8090914-A None JP disclosed
JP-8169181-A None JP disclosed
JP-8108627-A None JP disclosed
JP-7228050-A None JP disclosed
JP-8244346-A None JP disclosed
JP-7223366-A None JP disclosed
JP-H08244346-A REVERSIBLE THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1996-09-24 JP disclosed
JP-H08169181-A REVERSIBLY THERMOSENSIBLE RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1996-07-02 JP disclosed
JP-H08108627-A REVERSIBLE THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1996-04-30 JP disclosed
JP-H0890914-A REVERSIBLE THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1996-04-09 JP disclosed
JP-H07228050-A REVERSIBLE THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1995-08-29 JP disclosed
JP-H07223366-A REVERSIBLE THERMAL RECORDING MATERIAL MITSUBISHI PAPER MILLS LTD 1995-08-22 JP disclosed
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4188212-A BEZNOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1980-02-12 US disclosed
US-3933507-A LIGHT INSENSITIVE SILVER SALT, POLYMETHINE SENSITIZER AGFA-GEVAERT, A.G. (DT) 1976-01-20 US disclosed