Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.71 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.45 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8933916 | 0.83 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL860766 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL13776402 | 0.77 | PTGS2 (0.77) | PTGS2PTGS1F10 | |
| SCHEMBL5071832 | 0.75 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL8934224 | 0.75 | PTGS2 (0.84) | PTGS2PTGS1 | |
| SCHEMBL8934166 | 0.70 | PTGS2 (0.84) | PTGS2PTGS1 | |
| SCHEMBL8933879 | 0.69 | PTGS2 (0.82) | PTGS2PTGS1 | |
| SCHEMBL8934005 | 0.67 | PTGS2 (0.40) | PTGS2PTGS1F10 | |
| SCHEMBL8933882 | 0.66 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8472124 | 0.66 | PTGS2 (0.61) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565482-A | ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | G.D. SEARLE & CO. (US) | 1996-10-15 | — | — | US | disclosed |
| US-5547975-A | ANTIARTHRIC AGENTS, ANALGESICS AND ANTIPYRETICS; INHIBITORS OF CYCLOOXYGENASE II; SIDE EFFECT REDUCTION | G.D. SEARLE & CO. | 1996-08-20 | — | — | US | disclosed |