Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.61 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.31 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473278 | 0.79 | PTGS2 (0.42) | PTGS2MEN1KMT2APTGS1MAPT | |
| SCHEMBL5070956 | 0.78 | PTGS2 (0.77) | PTGS2PTGS1KDM4EALDH1A1 | |
| SCHEMBL8473205 | 0.76 | PTGS2 (0.39) | PTGS2PTGS1 | |
| SCHEMBL8933882 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1ALDH1A1 | |
| SCHEMBL8917762 | 0.73 | KAT6A (0.38) | PTGS2KAT6AMEN1KMT2APOLB | |
| SCHEMBL8689037 | 0.70 | ACHE (0.41) | MEN1KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL8916155 | 0.67 | HTR6 (0.36) | PTGS2MEN1KMT2APTGS1POLB | |
| SCHEMBL5071832 | 0.67 | PTGS2 (0.77) | PTGS2PTGS1POLBALDH1A1MAPT | |
| SCHEMBL8470424 | 0.67 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL8693427 | 0.66 | HTT (0.41) | MEN1KMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886016-A | ANTIINFLAMMATORY AGENT WITH MINIMAL SIDE EFFECTS FOR TREATING ARTHRITIS | G.D. SEARLE & CO. (US) | 1999-03-23 | — | — | US | disclosed |
| US-5670532-A | Pyrazolyl derivatives for the treatment of inflammation | G. D. SEARLE & CO. (US) | 1997-09-23 | — | — | US | disclosed |