Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 3/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937746 | 0.84 | KDM4E (0.41) | MAOAALDH1A1KDM4EHPGDNPSR1 | |
| SCHEMBL8937712 | 0.68 | MAOA (0.49) | MAOAALDH1A1KDM4EHPGDMAOB | |
| SCHEMBL2387712 | 0.58 | ERN1 (0.56) | ALDH1A1KDM4EHPGDMAPTGAA | |
| SCHEMBL1165033 | 0.57 | MAPT (0.43) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL3545 | 0.57 | L3MBTL1 (0.57) | ALDH1A1KDM4EHPGDTDP1MAPT | |
| SCHEMBL16291133 | 0.57 | L3MBTL1 (0.57) | ALDH1A1KDM4EHPGDTDP1MAPT | |
| SCHEMBL29805004 | 0.56 | MAOA (0.45) | MAOAALDH1A1KDM4EHPGDTDP1 | |
| SCHEMBL4344657 | 0.56 | LTA4H (0.52) | ALDH1A1KDM4EHPGDNPSR1TDP1 | |
| SCHEMBL12878267 | 0.56 | MAPT (0.49) | ALDH1A1KDM4EHPGDNPSR1MAPT | |
| SCHEMBL12679744 | 0.56 | ADORA2A (0.54) | ALDH1A1KDM4EHPGDNPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563166-A | Thienyl- and furylpyrrole fungicidal agents | AMERICAN CYANAMID CO. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5492925-A | PROTECTING PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5480902-A | Thienylpyrrole fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0641794-A1 | Thienyl- and furylpyrrole derivatives, their preparation and their use as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1995-03-08 | — | — | EP | disclosed |