Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449452 | 0.98 | LTA4H (0.50) | LTA4HCYP11B2CYP17A1CYP11B1KCNH2 | |
| SCHEMBL28485840 | 0.89 | HDAC2 (0.51) | LTA4HCYP11B2CYP17A1CYP11B1KCNH2 | |
| 4-(2,2'-Bithiophen-5-Yl)Benzonitrile SCHEMBL4344574 | 0.87 | PRF1 (0.46) | LTA4HKIF11KDM4EALDH1A1MEN1 | |
| SCHEMBL28669772 | 0.86 | ADORA2A (0.48) | CYP11B2KIF11KDM4EALDH1A1MEN1 | |
| SCHEMBL10964644 | 0.83 | KDM1A (0.47) | CYP11B2CYP11B1KDM4EALDH1A1MEN1 | |
| SCHEMBL10300120 | 0.83 | LTA4H (0.55) | LTA4HCYP11B2CYP17A1CYP11B1KCNH2 | |
| SCHEMBL7438158 | 0.82 | PRMT6 (0.50) | LTA4HKCNH2ALDH1A1MEN1KMT2A | |
| SCHEMBL10964561 | 0.82 | KDM1A (0.46) | CYP11B2CYP11B1KDM4EALDH1A1MEN1 | |
| SCHEMBL338810 | 0.82 | LTA4H (0.70) | LTA4HCYP11B2CYP17A1CYP11B1KCNH2 | |
| SCHEMBL15721607 | 0.82 | KCNH2 (0.44) | LTA4HKCNH2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114839366-A | Nanoparticle for detecting antigen protein and preparation method thereof | 南方科技大学 | 2022-08-02 | — | — | CN | claimed |
| CN-113441179-B | Thiophene modified covalent triazine framework material and preparation and application thereof | 浙江工业大学 | 2022-05-24 | — | — | CN | claimed |
| CN-113441179-A | Thiophene-modified covalent triazine framework material and preparation and application thereof | 浙江工业大学 | 2021-09-28 | — | — | CN | claimed |
| US-7517893-B2 | Bichalcophenes and their prodrugs as antiprotozoal agents | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-04-14 | — | — | US | claimed |
| EP-1726589-B1 | 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof | UNIV NORTH CAROLINA (US) | 2008-10-15 | — | — | EP | claimed |
| CN-1935797-A | Bichalcophenes and prodrugs thereof as antiprotozoal agents | UNIV NORTH CAROLINA (US) | 2007-03-28 | — | — | CN | claimed |
| US-20060293540-A1 | Novel bichalcophenes and their prodrugs as antiprotozoal agents | TIDWELL RICHARD R | 2006-12-28 | — | — | US | claimed |
| EP-1726589-A2 | 5,5'-bis-(4-amidinophenyl)-2,2'-bifuran derivatives and related compounds as antiprotozoal agent and prodrugs thereof | UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2006-11-29 | — | — | EP | claimed |
| US-20030060473-A1 | Piperazine compounds as inhibitors of MMP or TNF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-27 | — | — | US | claimed |
| WO-2003018019-A2 | NEW USE OF CYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-03-06 | — | — | WO | claimed |
| US-6489324-B2 | TREATING STROKE, ARHTRITIS, CANCER, TISSUE ULCERATION, DECUBITIS ULCER, RESTENOSIS, PERIODONTAL DISEASE, EPIDERMOLYSIS BULLOSA, SCLERITIS, PSORIASIS, AIDS, SEPSIS, AND SEPTIC SHOCK. | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-03 | — | — | US | claimed |
| US-20020128270-A1 | Piperazine compounds as inhibitors of MMP or TNF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-09-12 | — | — | US | claimed |
| US-6333324-B1 | FOR THERAPY AND PROPHYLAXIS OF MATRIX METALLOPROTEINASES (MMP) OR TUMOR NECROSIS FACTOR .ALPHA. (TNF.ALPHA.), MEDIATED DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-25 | — | — | US | claimed |
| EP-0948489-A1 | PIPERAZINE COMPOUNDS AS INHIBITORS OF MMP OR TNF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-13 | — | — | EP | claimed |
| WO-1998027069-A1 | PIPERAZINE COMPOUNDS AS INHIBITORS OF MMP OR TNF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-25 | — | — | WO | claimed |
| WO-2023224579-A1 | BISMUTHENE AS A VERSATILE PHOTOCATALYST OPERATING UNDER VARIABLE CONDITIONS FOR THE PHOTOREDOX C–H BOND FUNCTIONALIZATION | KOC UNIVERSITESI (TR) | 2023-11-23 | — | — | WO | disclosed |
| CN-116969952-A | Diphenyl pyrrolo-pyrrole-dione derivative and pigment composition thereof | 山东凯瑞尔光电科技有限公司 | 2023-10-31 | — | — | CN | disclosed |
| US-4778899-A | PIGMENTS USED IN PLASTICS OR LACQUERS; IMPROVED COLORFASTNESS | CIBA-GEIGY CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| US-4659775-A | COLORING ORGANIC MATERIALS OF HIGH MOLECULAR WEIGHT | CIBA-GEIGY CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0184982-A1 | Pyrrolo-[3,4-c]-pyrroles and process for their preparation | CIBA-GEIGY AG (CH) | 1986-06-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293540-A1 | Novel bichalcophenes and their prodrugs as antiprotozoal agents | CASP7, DDT, BAD | LTA4H 1269/4885CYP11B2 678/4885CYP17A1 4331/4885 |
| US-20020128270-A1 | Piperazine compounds as inhibitors of MMP or TNF | MMP1, MMP2, TNF | LTA4H 443/4885CYP11B2 1162/4885CYP17A1 821/4885 |
| US-20030060473-A1 | Piperazine compounds as inhibitors of MMP or TNF | MMP2, MMP1, TNF | LTA4H 371/4885CYP11B2 862/4885CYP17A1 700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.