Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 7/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2672559 | 0.94 | MMP8 (0.54) | MMP8PKMCDC7DBF4ALDH1A1 | |
| SCHEMBL971944 | 0.86 | MMP8 (0.50) | MMP8PKMCDC7DBF4ALDH1A1 | |
| SCHEMBL1312803 | 0.81 | MMP8 (0.62) | MMP8PKMALDH1A1TP53NPY1R | |
| SCHEMBL6640643 | 0.80 | CPB2 (0.46) | MMP8CDC7DBF4ALDH1A1NAMPT | |
| SCHEMBL5314193 | 0.79 | CYP1A2 (0.48) | MMP8PKMCDC7DBF4ALDH1A1 | |
| SCHEMBL2958476 | 0.79 | ALDH1A1 (0.50) | MMP8CDC7DBF4ALDH1A1NAMPT | |
| SCHEMBL27231720 | 0.78 | EPHX2 (0.52) | CDC7DBF4NAMPTCYP19A1KMT2A | |
| SCHEMBL2370593 | 0.78 | CYP19A1 (0.45) | MMP8CDC7DBF4ALDH1A1NAMPT | |
| SCHEMBL6646153 | 0.78 | NAMPT (0.47) | MMP8CDC7DBF4ALDH1A1NAMPT | |
| SCHEMBL165382 | 0.76 | MMP8 (0.76) | MMP8PKMALDH1A1TP53NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663834-A4 | GROWTH HORMONE RELEASING PEPTIDES. | SMITHKLINE BEECHAM CORP (US) | 1996-01-24 | — | — | EP | disclosed |
| EP-0663834-A1 | GROWTH HORMONE RELEASING PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994007519-A1 | GROWTH HORMONE RELEASING PEPTIDES | SMITHKLINE BEECHAM CORPORATION (US) | 1994-04-14 | — | — | WO | disclosed |