Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 5/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.43 |
| ▸ | NAMPT | P43490 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8574971 | 0.87 | EPHX2 (0.51) | LMNAEPHX2PPARGMMP8KMT2A | |
| SCHEMBL2370593 | 0.85 | CYP19A1 (0.45) | ALDH1A1CYP3A4CYP19A1MAPTLMNA | |
| SCHEMBL6640643 | 0.84 | CPB2 (0.46) | ALDH1A1CYP19A1MAPTEPHX2PPARG | |
| SCHEMBL2672559 | 0.84 | MMP8 (0.54) | ALDH1A1CYP19A1MAPTCDC7DBF4 | |
| SCHEMBL20126694 | 0.84 | ALDH1A1 (0.55) | ALDH1A1CYP3A4CYP19A1MAPTLMNA | |
| SCHEMBL27231867 | 0.83 | CYP19A1 (0.44) | ALDH1A1CYP3A4CYP19A1MAPTLMNA | |
| SCHEMBL5314193 | 0.83 | CYP1A2 (0.48) | ALDH1A1CYP3A4CYP19A1MAPTCDC7 | |
| SCHEMBL1892061 | 0.82 | MMP8 (0.59) | ALDH1A1CYP3A4LMNAMAPK1EPHX2 | |
| SCHEMBL12311754 | 0.82 | MMP8 (0.59) | ALDH1A1CYP3A4LMNAMAPK1EPHX2 | |
| SCHEMBL15933208 | 0.82 | PPARG (0.48) | ALDH1A1MAPTLMNAEPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217932-A1 | PYRIDIUM ESTERS | THE PROCTER AND GAMBLE COMPANY | 2024-07-04 | — | — | US | disclosed |
| EP-4374698-A1 | PYRIDINIUM ESTERS | The Procter & Gamble Company (US) | 2024-05-29 | — | — | EP | disclosed |
| US-7767665-B2 | 3-[6-(4-oxo-4H-1,3-benzothiazin-2-yl)-2-pyridyl]propionic acid, having an excellent apoptosis inhibitory and Macrophage migration inhibitory factor (MIF) binding effects, used for preventing and/or treating cancers, AIDS, cardiovascular, neurodegeneartive, bone, kidney and liver disoders | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-03 | — | — | US | disclosed |
| US-20090082343-A1 | 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-03-26 | — | — | US | disclosed |
| US-7399759-B2 | 1, 3-benzothiazinone derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-07-15 | — | — | US | disclosed |
| US-20050032786-A1 | 1, 3-benzothiazinone derivatives and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-02-10 | — | — | US | disclosed |
| EP-1424336-A1 | 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-06-02 | — | — | EP | disclosed |
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082343-A1 | 1,3-BENZOTHIAZINONE DERIVATIVES AND USE THEREOF | MIF, MORF4L1, FOXM1 | ALDH1A1 273/4885CYP3A4 1744/4885CYP19A1 2619/4885 |
| US-20240217932-A1 | PYRIDIUM ESTERS | C5, CBR3, CHRM1 | ALDH1A1 2024/4885CYP3A4 68/4885CYP19A1 782/4885 |
| US-20050032786-A1 | 1, 3-benzothiazinone derivatives and use thereof | MIF, MORF4L1, FOXM1 | ALDH1A1 273/4885CYP3A4 1744/4885CYP19A1 2619/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.