Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937746 | 0.75 | KDM4E (0.41) | KMT2AMEN1KDM4EALDH1A1NPC1 | |
| SCHEMBL9019088 | 0.72 | KMT2A (0.43) | KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8937646 | 0.70 | MAOA (0.39) | KMT2AKDM4ESMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL8937621 | 0.68 | KDM4E (0.47) | KMT2AMEN1KDM4ESMN1; SMN2PTPN1 | |
| SCHEMBL7489462 | 0.64 | EGFR (0.52) | KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8937584 | 0.63 | KDM4E (0.48) | KMT2AMEN1KDM4ESMN1; SMN2PTPN1 | |
| SCHEMBL8937712 | 0.62 | MAOA (0.49) | KMT2AMEN1KDM4ESMN1; SMN2PTPN1 | |
| SCHEMBL8937617 | 0.61 | SMN1; SMN2 (0.41) | KMT2AMEN1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL3756657 | 0.61 | PTPN1 (0.50) | KMT2AMEN1KDM4EPTPN1ALDH1A1 | |
| SCHEMBL4488653 | 0.60 | ERCC1 (0.38) | KMT2AMEN1KDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563166-A | Thienyl- and furylpyrrole fungicidal agents | AMERICAN CYANAMID CO. (US) | 1996-10-08 | — | — | US | disclosed |
| US-5492925-A | PROTECTING PLANTS | AMERICAN CYANAMID COMPANY (US) | 1996-02-20 | — | — | US | disclosed |
| US-5480902-A | Thienylpyrrole fungicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-02 | — | — | US | disclosed |
| EP-0641794-A1 | Thienyl- and furylpyrrole derivatives, their preparation and their use as insecticides and acaricides | AMERICAN CYANAMID COMPANY (US) | 1995-03-08 | — | — | EP | disclosed |