Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL983062 | 0.79 | SMN1; SMN2 (0.33) | SMN1; SMN2L3MBTL1MAPTGCGRHPGD | |
| SCHEMBL11121321 | 0.77 | USP7 (0.39) | USP7SMN1; SMN2DHODHGCGRHPGD | |
| SCHEMBL9559655 | 0.75 | KMT2A (0.32) | SMN1; SMN2MAPTHPGD | |
| SCHEMBL9559699 | 0.71 | HPGD (0.44) | SMN1; SMN2MAPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9806251 | 0.71 | PDCD1 (0.47) | USP7SMN1; SMN2GCGRHPGDALDH1A1 | |
| SCHEMBL891578 | 0.70 | LMNA (0.36) | MAPTHPGDALDH1A1 | |
| SCHEMBL4621655 | 0.70 | ALDH1A1 (0.39) | SMN1; SMN2L3MBTL1MAPTHPGDTAAR1 | |
| SCHEMBL9559675 | 0.69 | HPGD (0.46) | SMN1; SMN2MAPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9559710 | 0.69 | HPGD (0.46) | SMN1; SMN2MAPTCHRNB2CHRNB4CHRNA3 | |
| SCHEMBL984059 | 0.69 | KDM4E (0.37) | SMN1; SMN2MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |