Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938028 | 0.79 | USP7 (0.35) | SMN1; SMN2TP53ESR1ESR2L3MBTL1 | |
| SCHEMBL984059 | 0.79 | KDM4E (0.37) | SMN1; SMN2MAPTKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8072396 | 0.79 | — | — | |
| SCHEMBL982140 | 0.77 | GABRA1 (0.35) | SMN1; SMN2TP53L3MBTL1MAPTHPGD | |
| SCHEMBL982136 | 0.76 | HSD11B1 (0.39) | ADORA3GCGR | |
| SCHEMBL9582176 | 0.75 | GABRA1 (0.36) | ADORA3 | |
| SCHEMBL10497051 | 0.75 | KDM5A (0.34) | MAPTKDM5AALDH1A1 | |
| SCHEMBL985492 | 0.73 | NR3C2 (0.36) | SMN1; SMN2POLBESR1ESR2MAPT | |
| SCHEMBL8677546 | 0.70 | AURKA (0.35) | SMN1; SMN2POLBMAPTNPC1RAB9A | |
| SCHEMBL983989 | 0.70 | LTA4H (0.38) | SMN1; SMN2POLBL3MBTL1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020158205-A1 | SULFUR-CONTAINING EXTREME-PRESSURE AGENT AND METAL WORKING OIL | DIC株式会社 | 2020-08-06 | — | — | WO | disclosed |
| EP-3684895-A1 | HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY | ExxonMobil Research and Engineering Company (US) | 2020-07-29 | — | — | EP | disclosed |
| WO-2020131439-A1 | GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2019055291-A1 | HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2019-03-21 | — | — | WO | disclosed |
| EP-2275406-B1 | PROCESS FOR PRODUCING ISOCYANATE | ASAHI CHEMICAL IND (JP) | 2018-11-28 | — | — | EP | disclosed |
| US-9233918-B2 | Isocyanate production process | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-01-12 | — | — | US | disclosed |
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| EP-2275406-A1 | PROCESS FOR PRODUCING ISOCYANATE | Asahi Kasei Chemicals Corporation (JP) | 2011-01-19 | — | — | EP | disclosed |
| US-4251435-A | FOR POLYOLEFINS | THE B. F. GOODRICH COMPANY (US) | 1981-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092731-A1 | ISOCYANATE PRODUCTION PROCESS | CPS1, PHGDH, APEH | SMN1; SMN2 4174/4885POLB 2481/4885RECQL 3210/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.