Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4561509 | 0.80 | EPHX1 (0.49) | KMT2ATDP1EPHX1LMNA | |
| SCHEMBL4561865 | 0.78 | LMNA (0.57) | ADRA1AEPHX1SIGMAR1LMNA | |
| SCHEMBL6740564 | 0.77 | KMT2A (0.51) | KMT2AMEN1TDP1EPHX1 | |
| SCHEMBL8938105 | 0.77 | SMN1; SMN2 (0.43) | KMT2ADRD2DRD3EPHX1LMNA | |
| SCHEMBL21644503 | 0.77 | GLS (0.48) | KMT2ADRD2DRD3EPHX1LMNA | |
| SCHEMBL29133806 | 0.75 | LMNA (0.57) | DRD4KMT2AMEN1KDM4EDRD2 | |
| SCHEMBL20538944 | 0.75 | LMNA (0.43) | KMT2AMEN1PPARGEPHX1LMNA | |
| SCHEMBL7556093 | 0.74 | GLS (0.43) | KMT2AMEN1KDM4EDRD2DRD3 | |
| SCHEMBL6624926 | 0.74 | GLS (0.50) | KMT2AHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL8938149 | 0.74 | ALDH1A1 (0.45) | DRD4KDM4EDRD2DRD3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |