Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938122 | 0.91 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2ADRB1ADRA1AALOX15 | |
| Hydrochloric Acid SCHEMBL8938094 | 0.83 | PNMT (0.49) | ALDH1A1ALOX15CYP3A4FAAHKDM4E | |
| SCHEMBL8938153 | 0.78 | ALOX15 (0.48) | ALDH1A1SMN1; SMN2ADRB1ADRB2ALOX15 | |
| SCHEMBL8938126 | 0.77 | ALOX15 (0.53) | ALDH1A1SMN1; SMN2ADRB1ADRB2ALOX15 | |
| SCHEMBL8938141 | 0.77 | ADRB3 (0.54) | ADRB1ADRB2ADRB3 | |
| SCHEMBL9193546 | 0.75 | ALOX15 (0.61) | ADRB1ADRB2DRD2DRD3ALOX15 | |
| SCHEMBL11741392 | 0.75 | HIF1A (0.49) | ALDH1A1SMN1; SMN2ADRB1ADRB2DRD3 | |
| SCHEMBL8938095 | 0.74 | PNMT (0.49) | ALDH1A1ALOX15FAAHKDM4EGAA | |
| SCHEMBL8938140 | 0.74 | DRD4 (0.46) | DRD2DRD3ADRA1AHTR1ADRD4 | |
| SCHEMBL9192309 | 0.73 | ALOX15 (0.76) | SMN1; SMN2ADRB1ALOX15ADRB3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |