Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938110 | 0.80 | HDAC8 (0.53) | KMT2AMEN1KDM4EHDAC8HDAC3 | |
| SCHEMBL11111266 | 0.77 | GAA (0.62) | KMT2AMEN1TDP1HDAC8HDAC3 | |
| SCHEMBL7424713 | 0.76 | NPC1 (0.62) | KMT2AMEN1KDM4EHDAC8HDAC3 | |
| SCHEMBL29133806 | 0.76 | LMNA (0.57) | DRD4KMT2AMEN1KDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL11105183 | 0.76 | GAA (0.60) | KMT2AMEN1TDP1HDAC8HDAC3 | |
| Bromide SCHEMBL11105861 | 0.76 | GAA (0.60) | KMT2AMEN1TDP1HDAC8HDAC3 | |
| SCHEMBL28308722 | 0.75 | KMT2A (0.55) | KMT2AMEN1KDM4EHDAC8HDAC6 | |
| SCHEMBL28139812 | 0.74 | MEN1 (0.60) | KMT2AMEN1KDM4EHDAC8HDAC3 | |
| SCHEMBL8976099 | 0.74 | DRD4 (0.65) | DRD4KMT2AKDM4EHDAC8HDAC3 | |
| Bicarbonate SCHEMBL11577700 | 0.73 | MEN1 (0.81) | DRD4KMT2AMEN1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |