Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | CNR2 | P34972 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424713 | 0.81 | NPC1 (0.62) | HDAC8HDAC6MEN1KMT2AEPHX2 | |
| SCHEMBL8938142 | 0.80 | DRD4 (0.50) | HDAC8HDAC6MEN1KMT2AALDH1A1 | |
| SCHEMBL28308722 | 0.80 | KMT2A (0.55) | HDAC8HDAC6MEN1KMT2AEPHX2 | |
| SCHEMBL28139812 | 0.79 | MEN1 (0.60) | HDAC8HDAC6MEN1KMT2AEPHX2 | |
| SCHEMBL14821325 | 0.77 | ITGB3 (0.59) | HDAC6ALDH1A1KDM4ELMNAITGB3 | |
| SCHEMBL23067457 | 0.76 | CA12 (0.58) | KMT2AALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL10625988 | 0.76 | MEN1 (0.51) | HDAC8HDAC6MEN1KMT2AEPHX2 | |
| Hydrochloric Acid SCHEMBL14812031 | 0.76 | ITGB3 (0.58) | HDAC6ALDH1A1KDM4ELMNAITGB3 | |
| SCHEMBL5169062 | 0.76 | ALDH1A1 (0.62) | MEN1KMT2ACNR2ALDH1A1MAPT | |
| SCHEMBL1600243 | 0.76 | MEN1 (0.59) | HDAC8HDAC6MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5502078-A | Chemical compounds | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |