Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938407 | 0.91 | AKR1B1 (0.43) | AKR1B1FABP4CA2POLBKDM4E | |
| SCHEMBL1403662 | 0.84 | FABP4 (0.56) | AKR1B1FABP4CA2POLBMAPT | |
| SCHEMBL11694491 | 0.84 | AKR1B1 (0.46) | AKR1B1CA2POLBKDM4EMAPT | |
| SCHEMBL9480637 | 0.80 | CYP4F2 (0.42) | POLBKDM4ERAB9ANPC1CASP3 | |
| Formic Acid SCHEMBL28322635 | 0.79 | RAB9A (0.54) | AKR1B1FABP4POLBMAPTRAB9A | |
| SCHEMBL9327652 | 0.78 | CTNNB1 (0.55) | AKR1B1FABP4POLBHPGDHSD17B10 | |
| SCHEMBL8938493 | 0.78 | ALDH1A1 (0.39) | CA2POLBKDM4EMAPTGAA | |
| SCHEMBL18149084 | 0.78 | RAB9A (0.35) | POLBMAPTRAB9ANPC1CASP3 | |
| SCHEMBL28071044 | 0.76 | ALDH1A1 (0.49) | FABP4CA2POLBKDM4EMAPT | |
| SCHEMBL5233065 | 0.74 | AKR1B1 (0.49) | AKR1B1CA2POLBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534626-A | SELECTIVE MUSCARINIC RECEPTOR ANTAGONIST INTERMEDIATES | PFIZER INC. (US) | 1996-07-09 | — | — | US | disclosed |
| EP-0510003-B1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES | PFIZER LTD (GB) | 1995-09-27 | — | — | EP | disclosed |
| US-5410046-A | Selective muscarinic receptor antagonists | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5344835-A | Muscarinic receptor antagonists, smooth muscle relaxants, irritable bowel syndrome | PFIZER INC. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5302595-A | Muscarinic receptor antagonists | PFIZER INC. (US) | 1994-04-12 | — | — | US | disclosed |
| EP-0388054-B1 | Pyrrolidine derivatives | PFIZER LTD (GB) | 1993-11-03 | — | — | EP | disclosed |
| US-5233053-A | Pyrrolidine derivatives | PFIZER INC. (US) | 1993-08-03 | — | — | US | disclosed |
| US-5231104-A | Anticholinergic | PFIZER INC. (US) | 1993-07-27 | — | — | US | disclosed |
| US-5219871-A | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1993-06-15 | — | — | US | disclosed |
| US-5192765-A | Smooth muscle, bowel, bladder and airway diseases | PFIZER INC. (US) | 1993-03-09 | — | — | US | disclosed |
| US-5096890-A | PYRROLIDINE DERIVATIVES | PFIZER INC. (US) | 1992-03-17 | — | — | US | disclosed |
| US-5089505-A | Anticholinergic agents | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0438533-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1991-07-31 | — | — | EP | disclosed |
| WO-1991010650-A1 | PIPERIDINE AND PYRROLIDINE DERIVATIVES | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |
| EP-0364123-B1 | MUSCARINIC RECEPTOR ANTAGONISTS | Pfizer Limited (GB) | 1991-06-12 | — | — | EP | disclosed |
| EP-0388054-A1 | Pyrrolidine derivatives | Pfizer Limited (GB) | 1990-09-19 | — | — | EP | disclosed |
| WO-1990004583-A1 | MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1990-05-03 | — | — | WO | disclosed |
| EP-0365093-A1 | Muscarinic receptor antagonists | PFIZER INC. (US) | 1990-04-25 | — | — | EP | disclosed |
| EP-0364123-A1 | Muscarinic receptor antagonists | Pfizer Limited (GB) | 1990-04-18 | — | — | EP | disclosed |
| EP-0350309-A1 | Piperidine derivatives | Pfizer Limited (GB) | 1990-01-10 | — | — | EP | disclosed |