Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 2/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990537 | 0.80 | GAA (0.40) | GAAALDH1A1MAPK1MDM4MDM2 | |
| SCHEMBL8938880 | 0.72 | IGF1R (0.54) | GAAALDH1A1MAPK1CYP3A4 | |
| SCHEMBL8938909 | 0.68 | CYP3A4 (0.35) | ALDH1A1CYP3A4 | |
| SCHEMBL28129775 | 0.68 | SIGMAR1 (0.55) | ALDH1A1MAPK1 | |
| SCHEMBL10450802 | 0.63 | CA12 (0.43) | CYP19A1 | |
| SCHEMBL27880552 | 0.63 | CYP26A1 (0.39) | ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL21962100 | 0.62 | — | — | |
| SCHEMBL8085206 | 0.62 | SLC6A2 (0.44) | CYP3A4CYP2D6 | |
| SCHEMBL30789061 | 0.61 | GAA (0.97) | GAAALDH1A1MAPK1LMNA | |
| SCHEMBL30789060 | 0.61 | GAA (0.97) | GAAALDH1A1MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543298-A | ADDING SPECIFIED COMPOUND TO LIQUID SAMPLE, MEASURING RATE OF AUTOOXIDATION SPECTROPHOTOMETRICALLY | OXIS INTERNATIONAL S.A. (FR) | 1996-08-06 | — | — | US | disclosed |